White button mushrooms (Agaricus bisporous) are the most common mushrooms sold in supermarkets. They are also known as button mushrooms, white mushrooms, or table mushrooms. Portobello and crimini mushrooms are more mature forms of Agaricus bisporous—as they age, white button mushrooms mature into cremini mushrooms (which are brown) and then into portobellos (also brown and much larger).
Of the mushrooms studied, white button mushrooms have among the most powerful breast cancer chemopreventive properties. Several studies have concluded that diets high in white button mushrooms may lower the risk of estrogen receptor-positive (ER+) breast cancer, especially in postmenopausal women, by reducing aromatase activity, a process by which androgens are converted to estrogens in the body. White button mushrooms have also been shown to inhibit the proliferation of ER+ breast cancer cells. However, they should be eaten cooked, not raw

Button Mushroom.

White button mushrooms are the most common type of mushroom consumed in the United States. They are a low-calorie, low-cholesterol, low-sodium food with a high fiber and protein content. Yee said they also offer a wide range of healthy ingredients, including vitamins such as thiamin and niacin; minerals such as iron, magnesium, manganese, zinc, and selenium; and powerful antioxidants. Most studies demonstrating the inverse relationship between white button mushroom consumption and breast cancer risk have been conducted in Asian countries, where their consumption is higher.

Chemicals in mushrooms have been found to slow the production of estrogen as well as DHT. The intake of mushrooms has also been found to reduce one type of negative regulation of immune function. By the latter mechanism, white button mushroom intake is thought to improve our immune function to fight cancer.

About Cancer.

Breast cancer is a major issue of investigation in drug discovery due to its rising frequency and global dominance. Plants are significant natural sources for the development of novel medications and therapies. Medicinal mushrooms have many biological response modifiers and are used for the treatment of many physical illnesses. In this research, a database of 89 macromolecules with anti-breast cancer activity, which were previously isolated from the mushrooms in the literature, has been selected for the three-dimensional quantitative structure-activity relationships (3D-QSAR) studies.The selected compounds from the mushroom were evaluated as potential breast cancer MCF-7 cell line inhibitors.

In the quest for promoting overall well-being, our dietary choices play a pivotal role, and one humble fungus species has been catching the spotlight in recent research: the white button mushroom (Agaricus biparous). Beyond its familiar presence on our dinner plates, this unassuming mushroom is emerging as a potential ally in the prevention of breast cancer, particularly in postmenopausal women.

Recent studies have unveiled the impressive chemopreventive properties of white button mushrooms, showcasing their unique ability to reduce the risk of estrogen receptor-positive (ER+) breast cancer. This is especially significant as ER+ breast cancer accounts for a substantial portion of breast cancer cases in postmenopausal women. The key lies in the mushrooms’ ability to inhibit aromatase activity, a crucial process where androgens are converted to estrogens in the body.